Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.1
USERS' SCORE
Good
Based on 19 Reviews
8.2
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)

Top Medical Research Studies

9
Lactobacillus reduces cold incidences
We evaluated the effectiveness of Lactobacillus casei strain Shirota in reducing upper respiratory tract infections (URTIs) among healthy middle-aged office workers. Over 12 weeks, 96 male participants consumed either fermented milk with LcS or a control milk.

Our findings showed a significant reduction in URTI episodes in those consuming the fermented milk—only 22.4% experienced infections compared to 53.2% in the control group. Furthermore, they had shorter illness durations and better immune responses. Overall, it seems that this daily intake can effectively reduce colds in healthy adults.
Read More
8
Lactobacillus benefits for common cold
We explored the effects of GCL1815, a lactic acid bacterium, on preventing common colds in a double-blind, randomized study with 200 participants.

Those taking GCL1815 experienced fewer symptoms like fever, fatigue, and nasal congestion compared to the placebo group.

The study suggests that GCL1815 activates dendritic cells, potentially enhancing our immune response to viruses. Overall, it appears that GCL1815 could be a promising aid for reducing common cold incidences in healthy adults.
Read More
8
Lactobacillus improves cold symptoms
We explored the effects of LG2055, a type of lactobacillus, on common cold symptoms in a study involving 200 healthy adults. Participants took either a yogurt containing LG2055 or a placebo for 12 weeks while completing daily health surveys.

The findings were promising; those consuming LG2055 reported fewer cold symptoms and showed improved immune markers. This suggests that incorporating LG2055 may help keep us feeling well during cold season by boosting our immune system.
Read More

Most Useful Reviews

9
Healthy for years
3 people found this helpful
I absolutely love this product! It has kept me healthy for two and a half years without catching even a common cold. The price keeps me coming back.
Read More
9
Effective for IBS
2 people found this helpful
I suffered from diarrhoea due to chronic IBS and nothing worked until I tried this probiotic. It was a miracle! I always take four tablets when I feel unwell and plan to keep buying it.
Read More
9
Immunity boost
2 people found this helpful
I order probiotics from different brands for my family regularly. Jarrow Formulas is one of the best in effectiveness and value. They regulate digestion and boost immunity; we’ve noticed fewer common colds since starting this.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.1
  • All Researches
9
Lactobacillus reduces cold incidences
We evaluated the effectiveness of Lactobacillus casei strain Shirota in reducing upper respiratory tract infections (URTIs) among healthy middle-aged office workers. Over 12 weeks, 96 male participants consumed either fermented milk with LcS or a control milk.

Our findings showed a significant reduction in URTI episodes in those consuming the fermented milk—only 22.4% experienced infections compared to 53.2% in the control group. Furthermore, they had shorter illness durations and better immune responses. Overall, it seems that this daily intake can effectively reduce colds in healthy adults.
Read More
9
Probiotics may lessen cold symptoms
We investigated whether daily probiotics, specifically Bifidobacterium longum, could help lessen the severity and duration of common cold symptoms over a three-month period.

In a well-structured study involving 479 healthy adults, we compared those taking probiotics with a control group. Our findings showed that the probiotic users experienced shorter cold episodes—by almost two days—and reported less severe symptoms, with clear improvements in their immune cells.

Overall, it seems that Bifidobacterium longum could offer a valuable aid in combating common colds.
Read More
9
Probiotic yogurt reduces cold symptoms
We investigated how consuming Qingrun yogurt, which contains the probiotic Bifidobacterium lactis, affects common colds among adults living in hazy areas. In a clinical trial with 136 participants, those who enjoyed the probiotic yogurt daily experienced fewer colds and reported milder symptoms compared to those who consumed regular yogurt.

Remarkably, it even shortened the duration and intensity of respiratory infections. The findings suggest that incorporating probiotic yogurt into our diets could be a beneficial strategy to help combat upper respiratory infections.
Read More
9
Probiotics reduce cold illness in children
We evaluated the effects of probiotic consumption on cold symptoms in healthy children aged 3 to 5 during winter. In our double-blind, placebo-controlled study with 326 participants, we found that those who received probiotics experienced a significant drop in fever, cough, and rhinorrhea incidence.

Specifically, the combination of Lactobacillus acidophilus and Bifidobacterium lactis significantly reduced fever by up to 72.7% and decreased cough incidence by 62.1%. Additionally, children on probiotics missed fewer days of child care, making it a promising strategy for managing cold symptoms in young kids.
Read More
8
Lactobacillus benefits for common cold
We explored the effects of GCL1815, a lactic acid bacterium, on preventing common colds in a double-blind, randomized study with 200 participants.

Those taking GCL1815 experienced fewer symptoms like fever, fatigue, and nasal congestion compared to the placebo group.

The study suggests that GCL1815 activates dendritic cells, potentially enhancing our immune response to viruses. Overall, it appears that GCL1815 could be a promising aid for reducing common cold incidences in healthy adults.
Read More

User Reviews

USERS' SCORE
Good
Based on 19 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Healthy for years
3 people found this helpful
I absolutely love this product! It has kept me healthy for two and a half years without catching even a common cold. The price keeps me coming back.
Read More
9
Effective for IBS
2 people found this helpful
I suffered from diarrhoea due to chronic IBS and nothing worked until I tried this probiotic. It was a miracle! I always take four tablets when I feel unwell and plan to keep buying it.
Read More
9
Immunity boost
2 people found this helpful
I order probiotics from different brands for my family regularly. Jarrow Formulas is one of the best in effectiveness and value. They regulate digestion and boost immunity; we’ve noticed fewer common colds since starting this.
Read More
9
Healthy kefir
1 people found this helpful
I recommend buying these probiotics in the cold season to ensure the bacteria are alive. I use them to make healthy kefir, which is a great treat!
Read More
9
Improved health
29 people found this helpful
It's simply the best probiotic. I had various digestive issues and frequent common colds until I discovered Jarrow Formulas. I seldom noticed any benefits from multiminerals. Now, I take a course once a year in spring and feel fantastic.
Read More

Frequently Asked Questions

9
Prevented colds
1 people found this helpful
I’ve taken Lactobacillus for about five months and I appreciate it. I didn’t get a cold this winter, which might be due to this probiotic.
7.5
Supports immunity
2 people found this helpful
These high-quality probiotics offer various strains for both adults and children. We take them as a family during the cold season, and they help maintain our immunity.
9
Effective for IBS
2 people found this helpful
I suffered from diarrhoea due to chronic IBS and nothing worked until I tried this probiotic. It was a miracle! I always take four tablets when I feel unwell and plan to keep buying it.
7.5
Prevented colds
5 people found this helpful
I'm prone to minor digestive problems and occasional IBS. I’ve tried pricier probiotics without difference. Since taking Jarrow, I’ve not caught a common cold in over three years. It might just be a coincidence; however, I feel healthier overall.
7.5
Enhanced immunity
1 people found this helpful
After taking this product, my immune system strengthened significantly, reducing the frequency of colds and cystitis. I plan to continue purchasing it, especially during sales.
9
Improved health
29 people found this helpful
It's simply the best probiotic. I had various digestive issues and frequent common colds until I discovered Jarrow Formulas. I seldom noticed any benefits from multiminerals. Now, I take a course once a year in spring and feel fantastic.
8
Lactobacillus benefits for common cold
We explored the effects of GCL1815, a lactic acid bacterium, on preventing common colds in a double-blind, randomized study with 200 participants.

Those taking GCL1815 experienced fewer symptoms like fever, fatigue, and nasal congestion compared to the placebo group.

The study suggests that GCL1815 activates dendritic cells, potentially enhancing our immune response to viruses. Overall, it appears that GCL1815 could be a promising aid for reducing common cold incidences in healthy adults.
9
Lactobacillus reduces cold incidences
We evaluated the effectiveness of Lactobacillus casei strain Shirota in reducing upper respiratory tract infections (URTIs) among healthy middle-aged office workers. Over 12 weeks, 96 male participants consumed either fermented milk with LcS or a control milk.

Our findings showed a significant reduction in URTI episodes in those consuming the fermented milk—only 22.4% experienced infections compared to 53.2% in the control group. Furthermore, they had shorter illness durations and better immune responses. Overall, it seems that this daily intake can effectively reduce colds in healthy adults.
7
Lactobacillus reduces inflammation, not virus
We explored how Lactobacillus rhamnosus affects the response of nasal epithelial cells to rhinovirus, the virus responsible for the common cold.

In our study, nasal cells from healthy adults were treated with different strains of L. rhamnosus before being infected with rhinovirus.

While L. rhamnosus did not alter viral replication or the production of certain inflammatory responses, it did reduce the secretion of pro-inflammatory mediators after infection.

Overall, while it may not stop the virus, L. rhamnosus seems to help dampen some of the cold's inflammatory effects.
8
Lactobacillus shows promise for colds
We examined how SBT2055, a lactobacillus treatment, impacts common cold symptoms in healthy adults. In a thorough randomized, double-blind, placebo-controlled trial with 200 participants, those taking SBT2055 reported improved symptom relief compared to the placebo group.

Participants experienced less runny nose, plugged nose, sneezing, sore throat, and chill. This suggests that lactobacillus can enhance immune response, especially in individuals with weakened immunity. Our findings reveal potential benefits of lactobacillus for those suffering from common cold symptoms.

References

  1. Watanabe I, Suzuki N, Takara T. Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study. Nutr Res. 2025;134:99. doi:10.1016/j.nutres.2024.12.004
  2. Wada H, Mawatari T, Saito Y, Azuma N, Iwama Y. Induces Two Types of Dendritic Cell Activation and Effectively Suppresses Onset of the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;17. doi:10.3390/nu17010101
  3. Yarlagadda T, Zhu Y, Snape N, Carey A, Bryan E, et al. Lactobacillus rhamnosus dampens cytokine and chemokine secretion from primary human nasal epithelial cells infected with rhinovirus. J Appl Microbiol. 2024;135. doi:10.1093/jambio/lxae018
  4. Kobatake E, Iwama Y, Arai T, Tsukisaka Y, Kabuki T. SBT2055 Activates Plasmacytoid Dendritic Cells and Improves Subjective Symptoms of Common Cold in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Comparative Trial. Nutrients. 2023;15. doi:10.3390/nu15204458
  5. Hemmi J, Makino S, Yokoo T, Kano H, Asami Y, et al. Consumption of yogurt fermented with ssp. OLL1073R-1 augments serum antibody titers against seasonal influenza vaccine in healthy adults. Biosci Microbiota Food Health. 2023;42:73. doi:10.12938/bmfh.2022-037
  6. Kobatake E, Iwama Y, Arai T, Shioya N, Kise M, et al. Intake of SBT2055 improves subjective symptoms of common cold during winter season in healthy adults: A randomized, double-blind, placebo-controlled parallel-group comparative study. Front Nutr. 2022;9:1063584. doi:10.3389/fnut.2022.1063584
  7. Gelardi M, La Mantia I, Drago L, Meroni G, Aragona SE, et al. A probiotic mixture in patients with upper respiratory diseases: the point of view of the otorhinolaringologist. J Biol Regul Homeost Agents. 2020;34:5.
  8. Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N. Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study. Eur J Nutr. 2020;59:409. doi:10.1007/s00394-019-02137-8
  9. Murata M, Kondo J, Iwabuchi N, Takahashi S, Yamauchi K, et al. Effects of paraprobiotic MCC1849 supplementation on symptoms of the common cold and mood states in healthy adults. Benef Microbes. 2018;9:855. doi:10.3920/BM2017.0197
  10. Zhang H, Yeh C, Jin Z, Ding L, Liu BY, et al. Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate. Synth Syst Biotechnol. 2018;3:113. doi:10.1016/j.synbio.2018.03.001
  11. Gleeson M, Bishop NC, Struszczak L. Effects of Lactobacillus casei Shirota ingestion on common cold infection and herpes virus antibodies in endurance athletes: a placebo-controlled, randomized trial. Eur J Appl Physiol. 2016;116:1555. doi:10.1007/s00421-016-3415-x
  12. Makino S, Sato A, Goto A, Nakamura M, Ogawa M, et al. Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. J Dairy Sci. 2016;99:915. doi:10.3168/jds.2015-10376
  13. Shida K, Sato T, Iizuka R, Hoshi R, Watanabe O, et al. Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers. Eur J Nutr. 2017;56:45. doi:10.1007/s00394-015-1056-1
  14. Kumpu M, Kekkonen RA, Korpela R, Tynkkynen S, Järvenpää S, et al. Effect of live and inactivated Lactobacillus rhamnosus GG on experimentally induced rhinovirus colds: randomised, double blind, placebo-controlled pilot trial. Benef Microbes. 2015;6:631. doi:10.3920/BM2014.0164
  15. Lehtoranta L, Kalima K, He L, Lappalainen M, Roivainen M, et al. Specific probiotics and virological findings in symptomatic conscripts attending military service in Finland. J Clin Virol. 2014;60:276. doi:10.1016/j.jcv.2014.03.021
  16. King S, Glanville J, Sanders ME, Fitzgerald A, Varley D. Effectiveness of probiotics on the duration of illness in healthy children and adults who develop common acute respiratory infectious conditions: a systematic review and meta-analysis. Br J Nutr. 2014;112:41. doi:10.1017/S0007114514000075
  17. Kato-Kataoka A, Nishida K, Takada M, Suda K, Kawai M, et al. Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress. Benef Microbes. 2016;7:153. doi:10.3920/BM2015.0100
  18. de Vrese M, Winkler P, Rautenberg P, Harder T, Noah C, et al. Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial. Clin Nutr. 2005;24:481.
  19. Zhang H, Miao J, Su M, Liu BY, Liu Z. Effect of fermented milk on upper respiratory tract infection in adults who lived in the haze area of Northern China: a randomized clinical trial. Pharm Biol. 2021;59:647. doi:10.1080/13880209.2021.1929344
  20. Turner RB, Woodfolk JA, Borish L, Steinke JW, Patrie JT, et al. Effect of probiotic on innate inflammatory response and viral shedding in experimental rhinovirus infection - a randomised controlled trial. Benef Microbes. 2017;8:207. doi:10.3920/BM2016.0160
  21. Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics. 2009;124:e172. doi:10.1542/peds.2008-2666
  22. Kokubo T, Wakai S, Fujiwara D, Kanauchi O, Jounai K, et al. Strain Plasma Improves Subjective Physical State and Presenteeism: A Randomized, Open-Label Crossover Study among Healthy Office Workers. Prev Nutr Food Sci. 2020;25:140. doi:10.3746/pnf.2020.25.2.140
  23. Sugimura T, Jounai K, Ohshio K, Tanaka T, Suwa M, et al. Immunomodulatory effect of Lactococcus lactis JCM5805 on human plasmacytoid dendritic cells. Clin Immunol. 2013;149:509. doi:10.1016/j.clim.2013.10.007
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